EZH1 antibody (N-Term)

Catalog No. ABIN2780390

This anti-EZH1 antibody is a Rabbit Polyclonal antibody detecting EZH1 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit and Zebrafish (Danio rerio).

Quick Overview for EZH1 antibody (N-Term) (ABIN2780390)

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EZH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EZH1 Antibody

Binding Specificity: N-Term

Sequence: MEIPNPPTSK CITYWKRKVK SEYMRLRQLK RLQANMGAKA LYVANFAKVQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against EZH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EZH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 747 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EZH1

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Alternative Name: EZH1

Background: EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity.
Alias Symbols: KIAA0388, KMT6B
Protein Interaction Partner: SUZ12, UBC, GATA4, esc, EED, EZH2, EZH1, ZMYND11, E2F6,
Protein Size: 747

Molecular Weight: 85 kDa

Gene ID: 2145

NCBI Accession: NM_001991, NP_001982

UniProt: Q92800