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EZH1 antibody (AA 160-280)

EZH1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7155475
  • Target See all EZH1 Antibodies
    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-280
    Reactivity
    • 56
    • 32
    • 23
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 53
    • 3
    • 1
    Rabbit
    Clonality
    • 54
    • 3
    Polyclonal
    Conjugate
    • 32
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EZH1 antibody is un-conjugated
    Application
    • 49
    • 28
    • 23
    • 13
    • 13
    • 11
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Mouse
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
    Isotype
    IgG
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  • Application Notes
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
    Alternative Name
    EZH1 (EZH1 Products)
    Synonyms
    KMT6B antibody, si:ch211-250i3.1 antibody, zgc:136829 antibody, AW557915 antibody, mKIAA0388 antibody, EZH1 antibody, enhancer of zeste 1 polycomb repressive complex 2 subunit antibody, EZH1 antibody, ezh1 antibody, Ezh1 antibody
    Background

    Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

    Aliases: Enhancer of zeste homolog 1 (Drosophila) antibody, Enhancer of zeste homolog 1 antibody, ENX-2 antibody, ENX2 antibody, Ezh1 antibody, EZH1_HUMAN antibody, Histone-lysine N-methyltransferase EZH1 antibody

    UniProt
    Q92800
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