GATA4 antibody (N-Term)

Catalog No. ABIN2780394

This anti-GATA4 antibody is a Rabbit Polyclonal antibody detecting GATA4 in WB. Suitable for Human, Rat, Mouse, Dog, Pig, Rabbit and Cow.

Quick Overview for GATA4 antibody (N-Term) (ABIN2780394)

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Reactivity: Human, Rat, Mouse, Dog, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GATA4 Antibody

Binding Specificity: N-Term

Sequence: MYQSLAMAAN HGPPPGAYEA GGPGAFMHGA GAASSPVYVP TPRVPSSVLG

Predicted Reactivity: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GATA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GATA4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 442 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GATA4

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Alternative Name: GATA4

Background: GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. GATA4is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.
Alias Symbols: ASD2, VSD1
Protein Interaction Partner: JARID2, NKX2-5, ZFPM2, KDM6A, EZH2, EZH1, SUZ12, SP1, HDAC2, Ep300, Cdk9, ZBTB3, ALX4, ID3, ID2, ID1, PIAS1, NFATC4, MED1, HAND2, MAPK3, TBX5, CRIP2, MEF2C, SRF, NR5A1, FOS, MAPK1, MDC1,
Protein Size: 442

Molecular Weight: 45 kDa

Gene ID: 2626

NCBI Accession: NM_002052, NP_002043

UniProt: Q5IFM8

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis