LMX1B antibody (C-Term)

Catalog No. ABIN2780417

This Rabbit Polyclonal antibody specifically detects LMX1B in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig and Rabbit.

Quick Overview for LMX1B antibody (C-Term) (ABIN2780417)

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMX1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LMX1B Antibody

Binding Specificity: C-Term

Sequence: QSPYGSSDPF QQGLTPPQMP GNDSIFHDID SDTSLTSLSD CFLGSSDVGS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LMX1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LMX1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LMX1B

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Alternative Name: LMX1B

Background: LMX1B is essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Defects in LMX1B are the cause of nail-patella syndrome (NPS) also knowan as Onychoosteodysplasia.
Alias Symbols: NPS1, LMX1.2
Protein Interaction Partner: LDB1, APP, SSBP3, TCF3,
Protein Size: 372

Molecular Weight: 42 kDa

Gene ID: 4010

NCBI Accession: NM_002316, NP_002307

UniProt: Q6ISC9

Pathways: Dopaminergic Neurogenesis