MXD1 antibody (N-Term)

Catalog No. ABIN2780418

Product Details anti-MXD1 Antibody

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio), Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAAAVRMNIQ MLLEAADYLE RREREAEHGY ASMLPYNNKD RDALKRRNKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MXD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 221 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MXD1

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Alternative Name: MXD1 (MXD1 Products)

Synonyms: MXD1 antibody, si:dkey-202n14.4 antibody, xmad1 antibody, BHLHC58 antibody, MAD antibody, MAD1 antibody, AW122478 antibody, Mad antibody, Mad1 antibody, Mad-1 antibody, MAX dimerization protein 1 antibody, MAX dimerization protein 1 L homeolog antibody, max dimerization protein 1 antibody, MXD1 antibody, mxd1 antibody, mxd1.L antibody, Mxd1 antibody

Background: MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. MXD1 competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor.MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAD, MAD1, MGC104659, BHLHC58
Protein Interaction Partner: HDAC2, MAX, VDR, APP, BIRC2, RPS6KB1, RPS6KA1, AKT1, SIN3A, KDM5A, SIN3B, PRAM1, SMC3, SAP30, MXD1, MYC, CD2, MYCL, MYCN, PML, MLX, HDAC1,
Protein Size: 221

Molecular Weight: 25 kDa

Gene ID: 4084

NCBI Accession: NM_002357, NP_002348

UniProt: Q0VFI9