MEIS1 antibody (N-Term)

Catalog No. ABIN2780423

This Rabbit Polyclonal antibody specifically detects MEIS1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for MEIS1 antibody (N-Term) (ABIN2780423)

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEIS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEIS1 Antibody

Binding Specificity: N-Term

Purpose: Meis1 Antibody - N-terminal region

Sequence: YGDPHAARSM QPVHHLNHGP PLHSHQYPHT AHTNAMAPSM GSSVNDALKR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Meis1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38148-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEIS1

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Alternative Name: Meis1

Background:

Background Information: Meis1 acts as a transcriptional regulator of PAX6 and a transcriptional activator of PF4 in complex with PBX1 or PBX2. It is required for hematopoiesis, megakaryocyte lineage development and vascular patterning. It may function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.

Gene Name: Meis homeobox 1

Alternative Symbols: Evi8, C530044H18Rik

Protein Name: Homeobox protein Meis1

Molecular Weight: 51kDa

Gene ID: 17268

NCBI Accession: NP_034919

UniProt: Q60954

Pathways: Chromatin Binding