Msx2/Hox8 antibody (N-Term)

Catalog No. ABIN2780427

This Rabbit Polyclonal antibody specifically detects Msx2/Hox8 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit and Goat.

Quick Overview for Msx2/Hox8 antibody (N-Term) (ABIN2780427)

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Msx2/Hox8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Msx2/Hox8 Antibody

Binding Specificity: N-Term

Purpose: MSX2 Antibody - N-terminal region

Sequence: MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MSX2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MSX2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105803

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Msx2/Hox8

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Alternative Name: MSX2

Background:

Background Information: MSX2 is a member of the muscle segment homeobox gene family. The protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

Gene Name: Msh homeobox 2

Alternative Symbols: FPP, MSH, PFM, CRS2, HOX8, PFM1

Protein Name: Homeobox protein MSX-2

Molecular Weight: 29kDa

Gene ID: 4488

NCBI Accession: NP_002440

UniProt: P35548