PBX2 antibody (C-Term)

Catalog No. ABIN2780441

This Rabbit Polyclonal antibody specifically detects PBX2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Dog, Horse, Cow, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PBX2 antibody (C-Term) (ABIN2780441)

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Horse, Cow, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PBX2 Antibody

Binding Specificity: C-Term

Sequence: PGGYGDNLGG GQMYSPREMR ANGSWQEAVT PSSVTSPTEG PGSVHSDTSN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PBX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PBX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 430 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PBX2

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Alternative Name: PBX2

Background: PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
Alias Symbols: G17, HOX12, PBX2MHC
Protein Interaction Partner: CARD9, HOXA1, SOX2, ELAVL1, COPS6, ZDHHC7, SKIV2L2, SMYD3, MCRS1, CCDC88B, RPS6KC1, PBX2, PBX1, CENPBD1, DCTN3, NUP62, BAIAP2, IKBKAP, UBE2E1, PKNOX1, BLOC1S1, RPL4, HOXB8, HOXA9,
Protein Size: 430

Molecular Weight: 46 kDa

Gene ID: 5089

NCBI Accession: NM_002586, NP_002577

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development