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TEF antibody (N-Term)

TEF Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Guinea Pig, Goat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780494
  • Target See all TEF Antibodies
    TEF (Thyrotrophic Embryonic Factor (TEF))
    Binding Specificity
    • 9
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 29
    • 27
    • 14
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Guinea Pig, Goat
    Host
    • 38
    • 1
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEF antibody is un-conjugated
    Application
    • 28
    • 20
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    PVDPQAGPGP GPGRAAGERG LSGSFPLVLK KLMENPPREA RLDKEKGKEK
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Goat: 91%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%, Sheep: 93%
    Characteristics
    This is a rabbit polyclonal antibody against TEF. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TEF
    Top Product
    Discover our top product TEF Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 303 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TEF (Thyrotrophic Embryonic Factor (TEF))
    Alternative Name
    TEF (TEF Products)
    Synonyms
    2310028D20Rik antibody, tef antibody, tefb antibody, tefbeta antibody, wu:fa12f02 antibody, wu:fb11h02 antibody, zTEF[a] antibody, VBP antibody, xtef antibody, TEF antibody, DKFZp459A027 antibody, dbp antibody, TEF2 antibody, zgc:112180 antibody, TEF, PAR bZIP transcription factor antibody, thyrotroph embryonic factor antibody, thyrotrophic embryonic factor a antibody, thyrotrophic embryonic factor antibody, D site of albumin promoter (albumin D-box) binding protein L homeolog antibody, thyrotrophic embryonic factor b antibody, TEF antibody, Tef antibody, tefa antibody, tef antibody, dbp.L antibody, tefb antibody
    Background
    TEF (thyrotroph embryonic factor) is a member of the PAR bZip (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. It accumulates with robust circadian rhythms in tissues with high amplitudes of clock gene expression.Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP), VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties.
    Alias Symbols: -
    Protein Interaction Partner: MRPL28, DBP,
    Protein Size: 303
    Molecular Weight
    33 kDa
    Gene ID
    7008
    NCBI Accession
    NM_003216, NP_003207
    UniProt
    Q10587
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