ZNF141 antibody (Middle Region)

Catalog No. ABIN2780523

This Rabbit Polyclonal antibody specifically detects ZNF141 in WB. It exhibits reactivity toward Human and Zebrafish (Danio rerio).

Quick Overview for ZNF141 antibody (Middle Region) (ABIN2780523)

Target: ZNF141 (Zinc Finger Protein 141 (ZNF141))

Reactivity: Human, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF141 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF141 Antibody

Binding Specificity: Middle Region

Purpose: ZNF141 Antibody - middle region

Sequence: KCKECDKAFK QFSLLSQHKK IHTVDKPYKC KDCDKAFKRF SHLNKHKKIH

Predicted Reactivity: Human: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against ZNF141. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZNF141

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38338-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF141

Target: ZNF141 (Zinc Finger Protein 141 (ZNF141))

Alternative Name: ZNF141

Background:

Background Information: Zinc finger encoding genes would be good candidates for being involved in the multiple developmental defects associated with chromosomal aneusomy--because of their role as transcriptional regulators, their abundance in the genome and their known association with specific developmental disorders. A zinc finger encoding cDNA (ZNF141) of the C2-H2/KRAB subfamily has been mapped to the 4p- (Wolf-Hirschhorn) syndrome (WHS) chromosome region. ZNF141 was expressed ubiquitously at low levels in the analysed tissue. The identification of a candidate gene for a chromosomal aneusomy syndrome belonging to a class of evolutionary conserved genes will provide options for studying its normal and abnormal expression during mammalian embryogenesis.

Gene Name: Zinc finger protein 141

Alternative Symbols: D4S90, pH Z-44

Protein Name: Zinc finger protein 141

Molecular Weight: 55kDa

Gene ID: 7700

NCBI Accession: NP_003432

UniProt: Q15928