EED antibody (N-Term)

Catalog No. ABIN2780548

The Rabbit Polyclonal anti-EED antibody (ABIN2780548) specifically detects EED in WB. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse and Rabbit samples.

Quick Overview for EED antibody (N-Term) (ABIN2780548)

Target: EED (Embryonic Ectoderm Development (EED))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EED antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EED Antibody

Binding Specificity: N-Term

Sequence: QKLSSDENSN PDLSGDENDD AVSIESGTNT ERPDTPTNTP NAPGRKSWGK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against EED. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EED

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 400 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EED

Target: EED (Embryonic Ectoderm Development (EED))

Alternative Name: EED

Background: EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function.
Alias Symbols: HEED, WAIT1
Protein Interaction Partner: PINK1, BRCA1, ADAM17, EZH2, IMP3, PSPC1, NAT10, PBRM1, RIF1, RBM28, HEATR1, MAGOHB, ARGLU1, MRPL20, NRDE2, CASZ1, BCOR, EXOSC4, LUC7L3, SF3B6, NOP58, SRRT, RAB14, C9orf114, CRNKL1, DDX47, HP1BP3, MYEF2, TRA2A, CPSF1, IGHV3-23, UTP20, PRPF19, ZNF638, RBMX,
Protein Size: 400

Molecular Weight: 45 kDa

Gene ID: 8726

NCBI Accession: NM_152991, NP_694536