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ZNF259 antibody (C-Term)

znf259 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Goat, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780558
  • Target See all ZNF259 (znf259) Antibodies
    ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))
    Binding Specificity
    • 9
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 40
    • 15
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Goat, Saccharomyces cerevisiae
    Host
    • 36
    • 4
    Rabbit
    Clonality
    • 37
    • 3
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNF259 antibody is un-conjugated
    Application
    • 33
    • 17
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GNSYLQNVYA PEDDPEMKVE RYKRTFDQNE ELGLNDMKTE GYEAGLAPQR
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against ZNF259. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF259
    Top Product
    Discover our top product znf259 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 459 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))
    Alternative Name
    ZNF259 (znf259 Products)
    Synonyms
    RGD1562173 antibody, zpr1 antibody, ZNF259 antibody, ZPR1 antibody, Zfp259 antibody, fc17g10 antibody, si:rp71-56i13.4 antibody, wu:fc17g10 antibody, zgc:56478 antibody, AI303781 antibody, Znf259 antibody, ZPR1 zinc finger antibody, ZPR1 zinc finger L homeolog antibody, Zpr1 antibody, ZPR1 antibody, zpr1 antibody, zpr1.L antibody
    Background
    ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.
    Alias Symbols: ZPR1
    Protein Interaction Partner: UBC, P3H1, FKBP10, RPRD1B, OSGEP, PPME1, SZRD1, ARIH1, HSPBP1, ACTR2, ACTR3, ARPC4, UBA2, TOM1L1, OGT, SURF2, PPP1R7, LPP, HSF1, AGFG1, HNRNPF, BAG1, ALAD, MPP3, SRXN1, NUDCD2, UBL7, THOC7, KLC2, UBQLN4, UFM1, UFC1, UBXN1, UHRF1, PHPT1, TES, UBXN7, HYPK,
    Protein Size: 459
    Molecular Weight
    51 kDa
    Gene ID
    8882
    NCBI Accession
    NM_003904, NP_003895
    UniProt
    O75312
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