IRF7 antibody (N-Term)

Catalog No. ABIN2780566

This anti-IRF7 antibody is a Rabbit Polyclonal antibody detecting IRF7 in WB. Suitable for Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Horse, Cow and Rabbit.

Quick Overview for IRF7 antibody (N-Term) (ABIN2780566)

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivity: Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRF7 Antibody

Binding Specificity: N-Term

Sequence: ISSGCYEGLQ WLDEARTCFR VPWKHFARKD LSEADARIFK AWAVARGRWP

Predicted Reactivity: Cow: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against IRF7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 164 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IRF7

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Alternative Name: IRF7

Background: IRF7 is interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue.IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.
Alias Symbols: IRF-7H, IRF7A
Protein Interaction Partner: UBC, SUMO2, SUMO3, TRAF6, NMI, DEAF1, MAFB, SMAD4, SMAD3, SMAD2, vIRF-1, Dlg4, PIAS4, INSR, GCLM, ACADS, MAVS, IRF7, IRF3, IRAK1, TBK1, TRIM28, SUMO1, EP300, CREBBP, TNFAIP3, TRIM21, P4HA1, ARAF, Gbp4, HACE1, CCDC47, TRMT61B, PALD1, TRMT2A, LTN1, TLK2, IQ
Protein Size: 164

Molecular Weight: 18 kDa

Gene ID: 3665

NCBI Accession: NM_004031, NP_004022

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy