AF9 antibody (N-Term)

Catalog No. ABIN2780604

The Rabbit Polyclonal anti-AF9 antibody is suitable to detect AF9 in samples from Human, Mouse, Cow, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio) and Guinea Pig. It has been validated for WB.

Quick Overview for AF9 antibody (N-Term) (ABIN2780604)

Target: AF9 (MLLT3) (Protein AF-9 (MLLT3))

Reactivity: Human, Mouse, Cow, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AF9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AF9 Antibody

Binding Specificity: N-Term

Purpose: MLLT3 Antibody - N-terminal region

Sequence: MASSCAVQVK LELGHRAQVR KKPTVEGFTH DWMVFVRGPE HSNIQHFVEK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MLLT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109228

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AF9

Target: AF9 (MLLT3) (Protein AF-9 (MLLT3))

Alternative Name: MLLT3

Background:

Background Information: MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9,11)(p22,q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.

Gene Name: Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 3

Alternative Symbols: AF9, YEATS3

Protein Name: Protein AF-9

Molecular Weight: 63kDa

Gene ID: 4300

NCBI Accession: NP_004520

UniProt: P42568