AF9 antibody (C-Term)

Catalog No. ABIN2780605

The Rabbit Polyclonal anti-AF9 antibody (ABIN2780605) specifically detects AF9 in WB. The antibody is reactive with Human, Mouse, Cow, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio) and Guinea Pig samples.

Quick Overview for AF9 antibody (C-Term) (ABIN2780605)

Target: AF9 (MLLT3) (Protein AF-9 (MLLT3))

Reactivity: Human, Mouse, Cow, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AF9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AF9 Antibody

Binding Specificity: C-Term

Sequence: ERHILQQIVN LIEETGHFHI TNTTFDFDLC SLDKTTVRKL QSYLETSGTS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MLLT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MLLT3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 342 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AF9

Target: AF9 (MLLT3) (Protein AF-9 (MLLT3))

Alternative Name: MLLT3

Background: MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9,11)(p22,q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.
Alias Symbols: AF9, FLJ2035, YEATS3
Protein Interaction Partner: CDK9, HSP90B1, EAF1, AFF4, ELL2, MED26, ELL, MLLT3, AFF1, MLLT1, CDK6, CCNT1, CCNT2, APP, Cbx8, DOT1L, PAF1, KMT2A, BCOR, MLLT10, RNF2, AFF3, EEF2, ACACA, PCGF1, ELL3, NIPBL, SIRT1, LRIF1, RBM48, APPBP2, MCM6, PTN, EEF1A1, SGK1,
Protein Size: 342

Molecular Weight: 37 kDa

Gene ID: 4300

NCBI Accession: NM_004529

UniProt: Q6LEQ8