PITX3 antibody (N-Term)

Catalog No. ABIN2780637

Product Details anti-PITX3 Antibody

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Sheep, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITX3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARSPALSLSD AGTPHPQLPE HGCKGQEHSD SEKASASLPG GSPEDGSLKK

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against PITX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PITX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 302 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PITX3

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Alternative Name: PITX3 (PITX3 Products)

Synonyms: CTPP4 antibody, CTRCT11 antibody, PTX3 antibody, pitx3 antibody, Ptx3 antibody, ak antibody, zgc:109716 antibody, pitx3-A antibody, xPitx3 antibody, paired like homeodomain 3 antibody, paired-like homeodomain 3 antibody, paired like homeodomain 3 L homeolog antibody, paired-like homeodomain transcription factor 3 antibody, paired-like homeodomain transcription factor Pitx3 antibody, PITX3 antibody, Pitx3 antibody, pitx3.L antibody, pitx3 antibody

Background: PITX3 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. Mutations of PITX3 have been associated with anterior segment mesenchymal dysgenesis (ASMD) and congenital cataracts. PITX3 is involved in lens formation during eye development.This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis (ASMD) and congenital cataracts. This protein is involved in lens formation during eye development.
Alias Symbols: PTX3, CTPP4
Protein Interaction Partner: PARK7, MTA1, SFPQ, NONO,
Protein Size: 302

Molecular Weight: 32 kDa

Gene ID: 5309

NCBI Accession: NM_005029, NP_005020

UniProt: O75364