PLA2G4B antibody (N-Term)

Catalog No. ABIN2780643

The Rabbit Polyclonal anti-PLA2G4B antibody (ABIN2780643) specifically detects PLA2G4B in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Cow, Rabbit and Guinea Pig samples.

Quick Overview for PLA2G4B antibody (N-Term) (ABIN2780643)

Target: PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G4B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLA2G4B Antibody

Binding Specificity: N-Term

Purpose: PLA2G4B Antibody - N-terminal region

Sequence: AEAALEAVRS ELREFPAAAR ELCVPLAVPY LDKPPTPLHF YRDWVCPNRP

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against PLA2G4B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLA2G4B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38556-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLA2G4B

Target: PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))

Alternative Name: PLA2G4B

Background:

Background Information: PLA2G4B gene transcribes naturally-occurring mRNAs that are co-transcribed products of the neighboring JMJD7 and PLA2G4B genes. Incompletely processed read-through transcripts from these two loci are abundantly expressed in most tissues, but the function of the predicted protein product has not yet been determined. Alternative splicing of this gene results in different transcript variants, some of which are candidates for nonsense-mediated decay (NMD).The LOC100137047-PLA2G4B mRNAs are naturally occurring co-transcribed products of the neighboring LOC100137047 and PLA2G4B genes. Incompletely processed read-through transcripts from these two loci are abundantly expressed in most tissues, but the function of the predicted protein product has not yet been determined. Alternative splicing of this gene results in different transcript variants, some of which are candidates for nonsense-mediated decay (NMD).

Gene Name: JMJD7-PLA2G4B readthrough

Alternative Symbols: HsT16992, cPLA2-beta

Protein Name: Cytosolic phospholipase A2 beta

Molecular Weight: 114kDa

Gene ID: 8681

NCBI Accession: NP_005081

UniProt: P0C869

Pathways: ER-Nucleus Signaling, VEGF Signaling