MAF antibody (C-Term)

Catalog No. ABIN2780676

This Rabbit Polyclonal antibody specifically detects MAF in WB and IHC. It exhibits reactivity toward Human and Horse.

Quick Overview for MAF antibody (C-Term) (ABIN2780676)

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAF Antibody

Binding Specificity: C-Term

Purpose: MAF Antibody - C-terminal region

Sequence: DAYKEKYEKL VSSGFRENGS SSDNPSSPEF FITEPTRKLE PSVGYATFWK

Predicted Reactivity: Horse: 93%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAF

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38608-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAF

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Alternative Name: MAF

Background:

Background Information: The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

Alternative Symbols: CCA4, AYGRP, c-MAF, CTRCT21

Protein Name: Transcription factor Maf

Molecular Weight: 42kDa

Gene ID: 4094

NCBI Accession: NP_005351

UniProt: O75444