TBX3 antibody (C-Term)

Catalog No. ABIN2780736

This anti-TBX3 antibody is a Rabbit Polyclonal antibody detecting TBX3 in WB. Suitable for Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for TBX3 antibody (C-Term) (ABIN2780736)

Target: TBX3 (T-Box 3 (TBX3))

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBX3 Antibody

Binding Specificity: C-Term

Sequence: SRSSTLSSSS MSLSPKLCAE KEAATSELQS IQRLVSGLEA KPDRSRSASP

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 86%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TBX3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TBX3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBX3

Target: TBX3 (T-Box 3 (TBX3))

Alternative Name: TBX3

Background: TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.
Protein Interaction Partner: CA8, AES, SOX2, Dlg4, ELAVL1, HDAC5, HDAC3, HDAC2, HDAC1, TOLLIP, TBX3,
Protein Size: 600

Molecular Weight: 66 kDa

Gene ID: 6926

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development