HDAC6 antibody (C-Term)
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- Target See all HDAC6 Antibodies
- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Cow, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
- Sequence
- VCHHEASEHP LVLSCVDLST WCYVCQAYVH HEDLQDVKNA AHQNKFGEDM
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against Hdac6. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac6
- Top Product
- Discover our top product HDAC6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1149 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HDAC6 (Histone Deacetylase 6 (HDAC6))
- Alternative Name
- Hdac6 (HDAC6 Products)
- Synonyms
- HD6 antibody, Hd6 antibody, Hdac5 antibody, Sfc6 antibody, mHDA2 antibody, CG6170 antibody, DHDAC2 antibody, DmHDAC2 antibody, Dmel\\CG6170 antibody, HDAC antibody, HDAC2 antibody, dHDAC2 antibody, dHDAC6 antibody, dmHDA404 antibody, hdac6 antibody, MGC53140 antibody, wu:fc31d02 antibody, dsim_GLEANR_17355 antibody, DsimGD17207 antibody, GD17207 antibody, HDAC6 antibody, ATHDA6 antibody, AXE1 antibody, HISTONE DEACETYLASE 6 antibody, MDC12.7 antibody, MDC12_7 antibody, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1 antibody, RPD3B antibody, RTS1 antibody, SIL1 antibody, histone deacetylase 6 antibody, histone deacetylase 6 antibody, Histone deacetylase 6 antibody, histone deacetylase 6 L homeolog antibody, GD17207 gene product from transcript GD17207-RB antibody, Histone DeAcetylase antibody, HDAC6 antibody, Hdac6 antibody, hdac6.L antibody, hdac6 antibody, Dsim\HDAC6 antibody, PTRG_03035 antibody, HDA6 antibody, hda-6 antibody
- Background
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Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Alias Symbols: Hd6, Hdac5, Sfc6, mHDA2
Protein Interaction Partner: Hdac11, Ubc, Hsp90ab1, Park2, TARDBP, Vcp, USP47, HDAC6, PLAA, GARS, Tuba1a, Rela, Nfkb1, Mapt,
Protein Size: 1149 - Molecular Weight
- 126 kDa
- Gene ID
- 15185
- NCBI Accession
- NM_010413, NP_034543
- UniProt
- Q9Z2V5
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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