PEG3 antibody (C-Term)

Catalog No. ABIN2780754

The Rabbit Polyclonal anti-PEG3 antibody has been validated for WB. It is suitable to detect PEG3 in samples from Human, Rat, Mouse, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for PEG3 antibody (C-Term) (ABIN2780754)

Target: PEG3 (Paternally Expressed 3 (PEG3))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PEG3 Antibody

Binding Specificity: C-Term

Sequence: FGECSGYIER ASTSTGGANQ ADEKYFKCDV CGQLFNDRLS LARHQNTHTG

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PEG3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1588 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Alternative Name: PEG3

Background: PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: PEG3, ALB, USP7, TRAF2, SIAH2, SIAH1, BRCA1,
Protein Size: 1588

Molecular Weight: 181 kDa

Gene ID: 5178

NCBI Accession: NM_006210, NP_006201

UniProt: Q9GZU2