PEG3 antibody (AA 1010-1090)

Catalog No. ABIN7223112

The Rabbit Polyclonal anti-PEG3 antibody (ABIN7223112) specifically detects PEG3 in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for PEG3 antibody (AA 1010-1090) (ABIN7223112)

Target: PEG3 (Paternally Expressed 3 (PEG3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PEG3 Antibody

Binding Specificity: AA 1010-1090

Purpose: Rabbit Anti-PEG3 Polyclonal Antibody

Specificity: PEG3 Polyclonal Antibody detects endogenous levels of PEG3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PEG3 at AA range: 1010-1090

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Alternative Name: PEG3

Background: PEG3, KIAA0287, ZSCAN24, Paternally-expressed gene 3 protein, Zinc finger and SCAN domain-containing protein 24In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID: 15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 181kD

Gene ID: 5178

UniProt: Q9GZU2