KAT5 antibody (N-Term)

Catalog No. ABIN2780772

This Rabbit Polyclonal antibody specifically detects KAT5 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Cow, Goat, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for KAT5 antibody (N-Term) (ABIN2780772)

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Goat, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KAT5 Antibody

Binding Specificity: N-Term

Purpose: HTATIP Antibody - N-terminal region

Sequence: EGCRLPVLRR NQDNEDEWPL AEILSVKDIS GRKLFYVHYI DFNKRLDEWV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HTATIP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTATIP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103600

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Alternative Name: HTATIP

Background:

Background Information: HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: K(lysine) acetyltransferase 5

Alternative Symbols: TIP, ESA1, PLIP, TIP60, cPLA2, HTATIP, ZC2HC5, HTATIP1, NEDFASB

Protein Name: Histone acetyltransferase KAT5

Molecular Weight: 62kDa

Gene ID: 10524

NCBI Accession: NP_874369

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway