Advillin antibody (Middle Region)

Catalog No. ABIN2780791

This Rabbit Polyclonal antibody specifically detects Advillin in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit and Pig.

Quick Overview for Advillin antibody (Middle Region) (ABIN2780791)

Target: Advillin (AVIL)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Advillin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Advillin Antibody

Binding Specificity: Middle Region

Purpose: AVIL Antibody - middle region

Sequence: QELPEDVNPA KKENYLSEQD FVSVFGITRG QFAALPGWKQ LQMKKEKGLF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against AVIL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AVIL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38822-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Advillin

Target: Advillin (AVIL)

Alternative Name: AVIL

Background:

Background Information: AVIL is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia.The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia.

Gene Name: Advillin

Alternative Symbols: p92, DOC6, ADVIL, NPHS21

Protein Name: Advillin

Molecular Weight: 92kDa

Gene ID: 10677

NCBI Accession: NP_006567

UniProt: O75366

Pathways: Regulation of Actin Filament Polymerization