LZTR1 antibody (N-Term)

Catalog No. ABIN2780806

The Rabbit Polyclonal anti-LZTR1 antibody has been validated for WB. It is suitable to detect LZTR1 in samples from Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig and Rabbit.

Quick Overview for LZTR1 antibody (N-Term) (ABIN2780806)

Target: LZTR1 (Leucine-Zipper-Like Transcription Regulator 1 (LZTR1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LZTR1 Antibody

Binding Specificity: N-Term

Sequence: AGPGSTGGQI GAAALAGGAR SKVAPSVDFD HSCSDSVEYL TLNFGPFETV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LZTR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LZTR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 840 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LZTR1

Target: LZTR1 (Leucine-Zipper-Like Transcription Regulator 1 (LZTR1))

Alternative Name: LZTR1

Background: Leucine-zipper-like transcriptional regulator 1(LZTR1) is belived to be a DNA-binding protein and transcriptional regulator based on its predicted structural characteristics. The transcript is present in several essential fetal organs and is hemizygously deleted in some DiGeorge syndrome patients. LZTR1 is thought to play a critical role in embryogenesis.This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.
Alias Symbols: LZTR-1, MGC21205, TCFL2
Protein Interaction Partner: LZTR1, TUBGCP4, CUL3, UBC, CNOT6L, ZNF584, ZNF714, ASB12, FANK1, TRIM5, KDM2B, L3MBTL3, POLR1B, ANKRD53, EHMT1, E2F8, PAPOLG, ZNF490, SND1, AATF, ZNF451, ZZZ3, SCMH1, ZBTB1, WWP1, RAI1, CEBPZ, SUGP2, NR1H3, CHAF1A, MED16, HDAC4, MED7, RUVBL1, IKBKG, ZNF17
Protein Size: 840

Molecular Weight: 95 kDa

Gene ID: 8216

NCBI Accession: NM_006767, NP_006758

UniProt: Q8N653