LZTR1 antibody (N-Term)

Catalog No. ABIN6991281

Product Details anti-LZTR1 Antibody

Target: LZTR1 (Leucine-Zipper-Like Transcription Regulator 1 (LZTR1))

Binding Specificity: AA 130-180, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: LZTR1 Antibody is affinity chromatography purified via peptide column.

Immunogen: LZTR1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human LZTR1. The immunogen is located within amino acids 130 - 180 of LZTR1.

Isotype: IgG

Application Details

Application Notes: LZTR1 antibody can be used for detection of LZTR1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LZTR1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LZTR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LZTR1

Target: LZTR1 (Leucine-Zipper-Like Transcription Regulator 1 (LZTR1))

Alternative Name: LZTR1 (LZTR1 Products)

Synonyms: LZTR1 antibody, DKFZp459B233 antibody, si:dkey-98f17.2 antibody, wu:fj87c05 antibody, zgc:158250 antibody, BTBD29 antibody, LZTR-1 antibody, 1200003E21Rik antibody, AI591627 antibody, AW550890 antibody, leucine-zipper-like transcriptional regulator 1 antibody, leucine zipper like transcription regulator 1 antibody, apoptosis inducing factor, mitochondria associated 3 antibody, leucine-zipper-like transcription regulator 1 antibody, leucine-zipper-like transcription regulator 1 L homeolog antibody, leucine-zipper-like transcriptional regulator, 1 antibody, LOC411262 antibody, LZTR1 antibody, AIFM3 antibody, lztr1 antibody, lztr1.L antibody, Lztr1 antibody

Background: LZTR1 Antibody: LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.

Gene ID: 8216

UniProt: Q8N653