ZNF197 antibody (Middle Region)

Catalog No. ABIN2780824

The Rabbit Polyclonal anti-ZNF197 antibody (ABIN2780824) specifically detects ZNF197 in WB. The antibody is reactive with Human, Horse, Cow, Dog, Pig and Rat samples.

Quick Overview for ZNF197 antibody (Middle Region) (ABIN2780824)

Target: ZNF197 (Zinc Finger Protein 197 (ZNF197))

Reactivity: Human, Horse, Cow, Dog, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF197 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF197 Antibody

Binding Specificity: Middle Region

Sequence: NLTVHQKIHT DEKPCECDVS EKEFSQTSNL HLQQKIHTIE EFSWLQNTNE

Predicted Reactivity: Cow: 93%, Dog: 83%, Horse: 85%, Human: 100%, Pig: 79%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against ZNF197. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZNF197

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1029 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF197

Target: ZNF197 (Zinc Finger Protein 197 (ZNF197))

Alternative Name: ZNF197

Background: ZNF197 belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described.
Alias Symbols: D3S1363E, P18, VHLaK, ZKSCAN9, ZNF166, ZNF20
Protein Interaction Partner: UBC, NDEL1, DISC1, ZNF197, TRIM28, VHL, HIF1A,
Protein Size: 1029

Molecular Weight: 119 kDa

Gene ID: 10168

NCBI Accession: NM_006991, NP_008922

UniProt: O14709