DP1 antibody (N-Term)

Catalog No. ABIN2780829

This Rabbit Polyclonal antibody specifically detects DP1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig and Rabbit.

Quick Overview for DP1 antibody (N-Term) (ABIN2780829)

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DP1 Antibody

Binding Specificity: N-Term

Sequence: NLSPGKGVVS LVAVHPSTVN TLGKQLLPKT FGQSNVNITQ QVVIGTPQRP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Tfdp1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 410 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DP1

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Alternative Name: Tfdp1

Background: Tfdp1 can stimulate E2F-dependent transcription. Tfdp1 binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Alias Symbols: Dp1, Drtf1
Protein Interaction Partner: L3mbtl2, Sertad1, SERTAD2, E2f1, Rnf2, Epc1, E2F6,
Protein Size: 410

Molecular Weight: 45 kDa

Gene ID: 21781

NCBI Accession: NM_009361, NP_033387

UniProt: Q08639

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases