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IKZF3 antibody (C-Term)

IKZF3 Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780887
  • Target See all IKZF3 Antibodies
    IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
    Binding Specificity
    • 15
    • 9
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 62
    • 33
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 51
    • 12
    Rabbit
    Clonality
    • 52
    • 11
    Polyclonal
    Conjugate
    • 37
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IKZF3 antibody is un-conjugated
    Application
    • 58
    • 28
    • 13
    • 13
    • 11
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LDYVMFTIHM GCHGFRDPFE CNMCGYRSHD RYEFSSHIAR GEHRALLK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against IKZF3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human IKZF3
    Top Product
    Discover our top product IKZF3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 509 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
    Alternative Name
    IKZF3 (IKZF3 Products)
    Synonyms
    AIO antibody, AIOLOS antibody, ZNFN1A3 antibody, aio antibody, aiolos antibody, znfn1a3 antibody, IKZF3 antibody, 5830411O07Rik antibody, Aiolos antibody, Zfpn1a3 antibody, Znfn1a3 antibody, IKAROS family zinc finger 3 antibody, IKAROS family zinc finger 3 L homeolog antibody, IKZF3 antibody, ikzf3.L antibody, Ikzf3 antibody
    Background
    IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
    Alias Symbols: AIOLOS, ZNFN1A3, AIO
    Protein Interaction Partner: STAMBPL1, EXOSC5, LGALS14, CABP5, PCID2, RCOR3, TBC1D22B, FANCL, MAGOHB, C1orf109, OAZ3, SPG21, CHCHD2, OSGIN1, POLM, PPP1R16B, ABLIM3, IKZF3, NEK6, FARS2, MRPL28, KAT5, BCAS2, AKAP9, FAM115A, EMC2, POLR1C, STX11, STK16, RAD51D, PSMA1, PRKAB2, PRKAA1, PIN
    Protein Size: 509
    Molecular Weight
    58 kDa
    Gene ID
    22806
    NCBI Accession
    NM_012481, NP_036613
    UniProt
    Q9UKT9
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