BRD7 antibody (C-Term)

Catalog No. ABIN2780896

Cited in 1 publication. The Rabbit Polyclonal anti-BRD7 antibody (ABIN2780896) specifically detects BRD7 in WB and IHC. The antibody is reactive with Human, Rat, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for BRD7 antibody (C-Term) (ABIN2780896)

Target: BRD7 (Bromodomain Containing 7 (BRD7))

Reactivity: Human, Rat, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BRD7 Antibody

Binding Specificity: C-Term

Purpose: BRD7 Antibody - C-terminal region

Sequence: KELAQQVTPG DIVSTYGVRK AMGISIPSPV MENNFVDLTE DTEEPKKTDV

Predicted Reactivity: Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against BRD7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39018-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-BRD7 antibody (ABIN2780896)

Zhou, Tan, Hershenson: "Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells." in: Respiratory physiology & neurobiology, Vol. 140, Issue 1, pp. 89-97, (2004) (PubMed).

Target Details for BRD7

Target: BRD7 (Bromodomain Containing 7 (BRD7))

Alternative Name: BRD7

Background:

Background Information: BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.

Gene Name: Bromodomain containing 7

Alternative Symbols: BP75, NAG4, CELTIX1

Protein Name: Bromodomain-containing protein 7

Molecular Weight: 74kDa

Gene ID: 29117

NCBI Accession: NP_037395

UniProt: Q9NPI1