OTX1 antibody (N-Term)

Catalog No. ABIN2780931

The Rabbit Polyclonal anti-OTX1 antibody is suitable to detect OTX1 in samples from Human, Rat, Mouse, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Sheep. It has been validated for WB.

Quick Overview for OTX1 antibody (N-Term) (ABIN2780931)

Target: OTX1 (Orthodenticle Homeobox 1 (OTX1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OTX1 Antibody

Binding Specificity: N-Term

Purpose: OTX1 Antibody - N-terminal region

Sequence: PRKQRRERTT FTRSQLDVLE ALFAKTRYPD IFMREEVALK INLPESRVQV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against OTX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OTX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39102-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for OTX1

Target: OTX1 (Orthodenticle Homeobox 1 (OTX1))

Alternative Name: OTX1

Background:

Background Information: OTX1 probably plays a role in the development of the brain and the sense organs. OTX1 can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.

Gene Name: Orthodenticle homeobox 1

Alternative Symbols: FLJ38361, MGC15736

Protein Name: Homeobox protein OTX1

Molecular Weight: 37kDa

Gene ID: 5013

NCBI Accession: NP_055377

UniProt: P32242