VSX1 antibody (N-Term)

Catalog No. ABIN2780933

The Rabbit Polyclonal anti-VSX1 antibody is suitable to detect VSX1 in samples from Human and Cow. It has been validated for WB.

Quick Overview for VSX1 antibody (N-Term) (ABIN2780933)

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VSX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VSX1 Antibody

Binding Specificity: N-Term

Purpose: VSX1 Antibody - N-terminal region

Sequence: MTGRDSLSDG RTSSRALVPG GSPRGSRPRG FAITDLLGLE AELPAPAGPG

Predicted Reactivity: Cow: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against VSX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VSX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115743

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for VSX1

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Alternative Name: VSX1

Background:

Background Information: VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Visual system homeobox 1

Alternative Symbols: PPD, KTCN, PPCD, RINX, KTCN1, PPCD1, CAASDS

Protein Name: Visual system homeobox 1

Molecular Weight: 25kDa

Gene ID: 30813

NCBI Accession: NP_955457

UniProt: Q9NZR4