CXXC1 antibody (C-Term)

Catalog No. ABIN2780935

This Rabbit Polyclonal antibody specifically detects CXXC1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Goat, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for CXXC1 antibody (C-Term) (ABIN2780935)

Target: CXXC1 (CXXC Finger Protein 1 (CXXC1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CXXC1 Antibody

Binding Specificity: C-Term

Purpose: CXXC1 Antibody - C-terminal region

Sequence: RVWYKLDELF EQERNVRTAM TNRAGLLALM LHQTIQHDPL TTDLRSSADR

Predicted Reactivity: Cow: 86%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CXXC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CXXC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098112

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CXXC1

Target: CXXC1 (CXXC Finger Protein 1 (CXXC1))

Alternative Name: CXXC1

Background:

Background Information: Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression.Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001).[supplied by OMIM].

Gene Name: CXXC finger protein 1

Alternative Symbols: CFP1, CGBP, SPP1, PCCX1, PHF18, hCGBP, ZCGPC1, HsT2645, 2410002I16Rik, 5830420C16Rik

Protein Name: CpG-binding protein

Molecular Weight: 76kDa

Gene ID: 30827

NCBI Accession: NP_055408

UniProt: Q9P0U4

Pathways: ER-Nucleus Signaling