KLHL5 antibody (N-Term)

Catalog No. ABIN405207

Cited in 1 publication. The Rabbit Polyclonal anti-KLHL5 antibody (ABIN405207) specifically detects KLHL5 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for KLHL5 antibody (N-Term) (ABIN405207)

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLHL5 Antibody

Binding Specificity: N-Term

Purpose: KLHL5 Antibody - N-terminal region

Sequence: MSGSRKEFDV KQILKIRWRW FGHQASSPNS TVDSQQGEFW NRGQTGANGG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against KLHL5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human KLHL5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39220-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-KLHL5 antibody (ABIN405207)

Nagalla, Shaw, Kong, Kondkar, Edelstein, Ma, Chen, McKnight, López, Yang, Jin, Bray, Leal, Dong, Bray: "Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity." in: Blood, Vol. 117, Issue 19, pp. 5189-97, (2011) (PubMed).

Target Details for KLHL5

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Alternative Name: KLHL5

Background:

Background Information: The kelch-repeat protein family is a recently found new kind of actin-binding protein. It is characterized by tandemly arranged motifs of about 50 amino acids. Most members of the kelch-repeat family were cytoskeletal proteins implicated in various cellular processes, such as actin cytoskeleton interaction, cytoplasmic sequestration of transcription factors and cell morphology. During the large-scale sequencing analysis of a human fetal brain cDNA library we found a novel kelch-like protein gene 5, KLHL5, KLHL5 has high identity with Drosophila kelch protein and many other family members. A novel splicing variants of KLHL5, named KLHL5b and the expression pattern of KLHL5b in many tissues.

Gene Name: Kelch-like 5 (Drosophila)

Alternative Symbols: -

Protein Name: Kelch-like protein 5

Molecular Weight: 79kDa

Gene ID: 51088

NCBI Accession: NP_001007076

UniProt: Q96PQ7