ERGIC2 antibody (N-Term)

Catalog No. ABIN2781015

This Rabbit Polyclonal antibody specifically detects ERGIC2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Pig and Zebrafish (Danio rerio).

Quick Overview for ERGIC2 antibody (N-Term) (ABIN2781015)

Target: ERGIC2 (ERGIC and Golgi 2 (ERGIC2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERGIC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERGIC2 Antibody

Binding Specificity: N-Term

Purpose: ERGIC2 Antibody - N-terminal region

Sequence: MRRLNRKKTL SLVKELDAFP KVPESYVETS ASGGTVSLIA FTTMALLTIM

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ERGIon Channel2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ERGIC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099794

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERGIC2

Target: ERGIC2 (ERGIC and Golgi 2 (ERGIC2))

Alternative Name: ERGIC2

Background:

Background Information: ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.

Gene Name: ERGIC and golgi 2

Alternative Symbols: PTX1, CDA14, Erv41, cd002

Protein Name: Endoplasmic reticulum-Golgi intermediate compartment protein 2

Molecular Weight: 43kDa

Gene ID: 51290

NCBI Accession: NP_057654

UniProt: Q96RQ1