NFKB Repressing Factor (NKRF) (N-Term) antibody

Details for Product No. ABIN2781031
Antigen
  • NKRF
  • NRF
  • nrf
  • itba4
  • 9430034D17Rik
  • AW124770
  • C80287
  • ITBA4
  • RGD1563950
  • NFKB repressing factor
  • NFKB repressing factor L homeolog
  • NF-kappaB repressing factor
  • NFKB repressing factor-like
  • NKRF
  • nkrf
  • nkrf.L
  • Nkrf
  • Nkrfl
Epitope
N-Term
4
3
3
3
3
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
52
25
15
7
7
6
6
6
5
3
2
2
1
Host
Rabbit
39
13
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
45
14
9
5
4
3
2
2
1
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NKRF
Sequence MEKILQMAEG IDIGEMPSYD LVLSKPSKGQ KRHLSTCDGQ NPPKKQAGSK
Predicted Reactivity Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against NKRF. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Antigen
Alternative Name NKRF (NKRF Antibody Abstract)
Background NKRF is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. NKRF localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.
Alias Symbols: NRF, ITBA4
Protein Interaction Partner: STAU1, UBC, XRN2, BMI1, TARDBP, BARD1, CAND1, COPS5, CUL1, CUL3, SIRT7, HNRNPA1, SUMO2, VHL, DHX58, PRKRA, SUMO1, HMOX2, BCL6, REL, RELA, NFKB2, NFKB1,
Protein Size: 388
Molecular Weight 44 kDa
Gene ID 55922
NCBI Accession NM_017544, NP_060014
UniProt O15226
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 388 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-NFKB Repressing Factor (NKRF) (N-Term) antibody (ABIN2781031) WB Suggested Anti-NKRF Antibody Titration: 2.5ug/ml ELISA Titer: 1:1562500 Positi...
Background publications Dreikhausen, Hiebenthal-Millow, Bartels, Resch, Nourbakhsh: "NF-kappaB-repressing factor inhibits elongation of human immunodeficiency virus type 1 transcription by DRB sensitivity-inducing factor." in: Molecular and cellular biology, Vol. 25, Issue 17, pp. 7473-83, 2005 (PubMed).

Did you look for something else?