Polybromo 1 antibody (Middle Region)

Catalog No. ABIN2781052

This Rabbit Polyclonal antibody specifically detects Polybromo 1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for Polybromo 1 antibody (Middle Region) (ABIN2781052)

Target: Polybromo 1 (PBRM1)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Polybromo 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Polybromo 1 Antibody

Binding Specificity: Middle Region

Purpose: PBRM1 Antibody - middle region

Sequence: SAESNSISKW DQTLAARRRD VHLSKEQESR LPSHWLKSKG AHTTMADALW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PBRM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PBRM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39332-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Polybromo 1

Target: Polybromo 1 (PBRM1)

Alternative Name: PBRM1

Background:

Background Information: PBRM1 is involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).

Gene Name: Polybromo 1

Alternative Symbols: PB1, BAF180

Protein Name: Protein polybromo-1

Molecular Weight: 181kDa

Gene ID: 55193

NCBI Accession: NP_060783

UniProt: Q86U86