ARNTL2 antibody (N-Term)

Catalog No. ABIN2781092

The Rabbit Polyclonal anti-ARNTL2 antibody is suitable to detect ARNTL2 in samples from Human, Mouse and Dog. It has been validated for WB and IHC.

Quick Overview for ARNTL2 antibody (N-Term) (ABIN2781092)

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ARNTL2 Antibody

Binding Specificity: N-Term

Purpose: ARNTL2 Antibody - N-terminal region

Sequence: PTAMGSFSSH MTEFPRKRKG SDSDPSQSGI MTEKVVEKLS QNPLTYLLST

Predicted Reactivity: Dog: 86%, Human: 100%, Mouse: 77%

Characteristics: This is a rabbit polyclonal antibody against ARNTL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARNTL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39398-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARNTL2

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Alternative Name: ARNTL2

Background:

Background Information: ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.

Gene Name: Aryl hydrocarbon receptor nuclear translocator-like 2

Alternative Symbols: CLIF, MOP9, BMAL2, PASD9, bHLHe6

Protein Name: Aryl hydrocarbon receptor nuclear translocator-like protein 2

Molecular Weight: 71 kDa

Gene ID: 56938

NCBI Accession: NP_064568

UniProt: Q8WYA1

Pathways: Photoperiodism