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CBX4 antibody (Middle Region)

CBX4 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio), Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781104
  • Target See all CBX4 Antibodies
    CBX4 (Chromobox Homolog 4 (CBX4))
    Binding Specificity
    • 15
    • 13
    • 10
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 66
    • 31
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio), Horse
    Host
    • 64
    • 2
    Rabbit
    Clonality
    • 64
    • 2
    Polyclonal
    Conjugate
    • 24
    • 7
    • 7
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CBX4 antibody is un-conjugated
    Application
    • 60
    • 41
    • 20
    • 14
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KWRGWSPKYN TWEPEENILD PRLLIAFQNR ERQEQLMGYR KRGPKPKPLV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CBX4. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human CBX4
    Top Product
    Discover our top product CBX4 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CBX4 (Chromobox Homolog 4 (CBX4))
    Alternative Name
    CBX4 (CBX4 Products)
    Synonyms
    MPc2 antibody, PC2 antibody, NBP16 antibody, XPolycomb antibody, cbx4-a antibody, im:6911625 antibody, zgc:158588 antibody, chromobox 4 antibody, chromobox 4 S homeolog antibody, chromobox homolog 4 antibody, chromobox homolog 4 (Pc class homolog, Drosophila) antibody, CBX4 antibody, Cbx4 antibody, cbx4.S antibody, cbx4 antibody
    Background
    CBX4 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. It monosumoylates ZNF131.
    Protein Interaction Partner: Rnf111, SUMO1, NEDD8, CBS, BMI1, EED, RNF2, HECW2, SOX2, YWHAE, YWHAB, CCDC158, DIS3L2, HIST4H4, CBX2, PARP12, RNF213, ZKSCAN7, DCAF6, KDM3A, MYCBP2, ANKRD26, PSME3, TRANK1, CBX4, HIST1H2AB, YWHAZ, SKIL, NPM1, HIST1H2BB, GTF2I, PHC2, CSNK2B, CSNK2A2, CSNK
    Protein Size: 290
    Molecular Weight
    31 kDa
    Gene ID
    8535
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