SOX17 antibody (Middle Region)

Catalog No. ABIN2781184

This Rabbit Polyclonal antibody specifically detects SOX17 in WB, IHC and FACS. It exhibits reactivity toward Human, Mouse, Dog, Rat and Guinea Pig.It has been mentioned in 1 publication

Quick Overview for SOX17 antibody (Middle Region) (ABIN2781184)

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reactivity: Human, Mouse, Dog, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-SOX17 Antibody

Binding Specificity: Middle Region

Purpose: SOX17 Antibody - middle region

Sequence: RTEFEQYLHF VCKPEMGLPY QGHDSGVNLP DSHGAISSVV SDASSAVYYC

Predicted Reactivity: Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SOX17. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX17

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39552-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SOX17 antibody (ABIN2781184)

Kallas, Pook, Trei, Maimets: "SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate." in: Stem cells international, Vol. 2014, pp. 298163, (2014) (PubMed).

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17

Background:

Background Information: The SOX17 gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.

Gene Name: SRY (sex determining region Y)-box 17

Alternative Symbols: VUR3

Protein Name: Transcription factor SOX-17

Molecular Weight: 44kDa

Gene ID: 64321

NCBI Accession: NP_071899

UniProt: Q9H6I2