SOX17 antibody (Middle Region)

Catalog No. ABIN2781184

This Rabbit Polyclonal antibody specifically detects SOX17 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog and Guinea Pigand has been mentioned in 1 publication.

Quick Overview for SOX17 antibody (Middle Region) (ABIN2781184)

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SOX17 Antibody

Binding Specificity: Middle Region

Sequence: RTEFEQYLHF VCKPEMGLPY QGHDSGVNLP DSHGAISSVV SDASSAVYYC

Predicted Reactivity: Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SOX17. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 414 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SOX17 antibody (ABIN2781184)

Kallas, Pook, Trei, Maimets: "SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate." in: Stem cells international, Vol. 2014, pp. 298163, (2014) (PubMed).

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17

Background: The SOX17 gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
Alias Symbols: FLJ22252, VUR3
Protein Interaction Partner: CTNNB1,
Protein Size: 414

Molecular Weight: 44 kDa

Gene ID: 64321

NCBI Accession: NM_022454, NP_071899

UniProt: Q9H6I2