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BCL11A antibody (C-Term)

BCL11A Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781193
  • Target See all BCL11A Antibodies
    BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
    Binding Specificity
    • 15
    • 15
    • 12
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 63
    • 35
    • 16
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 69
    • 9
    Rabbit
    Clonality
    • 60
    • 18
    Polyclonal
    Conjugate
    • 40
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL11A antibody is un-conjugated
    Application
    • 60
    • 24
    • 14
    • 13
    • 13
    • 10
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    YACAQSSKLT RHMKTHGQVG KDVYKCEICK MPFSVYSTLE KHMKKWHSDR
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against BCL11A. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human BCL11A
    Top Product
    Discover our top product BCL11A Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 835 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
    Alternative Name
    BCL11A (BCL11A Products)
    Synonyms
    2810047E18Rik antibody, BCL-11A antibody, Ctip1 antibody, D930021L15Rik antibody, Evi9 antibody, Evi9a antibody, Evi9b antibody, Evi9c antibody, mKIAA1809 antibody, BCL11A-L antibody, BCL11A-S antibody, BCL11A-XL antibody, BCL11a-M antibody, CTIP1 antibody, EVI9 antibody, HBFQTL5 antibody, ZNF856 antibody, bcl11a antibody, wu:fi09f10 antibody, zgc:136898 antibody, B cell CLL/lymphoma 11A (zinc finger protein) antibody, B-cell CLL/lymphoma 11A antibody, B-cell CLL/lymphoma 11A L homeolog antibody, B-cell CLL/lymphoma 11Aa antibody, Bcl11a antibody, BCL11A antibody, bcl11a.L antibody, bcl11aa antibody
    Background
    BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.
    Alias Symbols: BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
    Protein Interaction Partner: GMCL1P1, ZBTB24, NCK2, LMO1, NR2E3, NR2E1, NR2F2, NR2F1, NR2F6, HDAC2, HDAC1, CDCA3, YME1L1, CDK6, CDK4, ACTC1, APP, UBC, BCL6, BCL11A, Sumo1, SUMO2, SUMO3, SIRT1, MBD3, MTA2, MTA1, CHD4,
    Protein Size: 835
    Molecular Weight
    91 kDa
    Gene ID
    53335
    NCBI Accession
    NM_022893, NP_075044
    UniProt
    Q9H165
    Pathways
    Regulation of Cell Size
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