HOXB4 antibody (C-Term)

Catalog No. ABIN2781202

This Rabbit Polyclonal antibody specifically detects HOXB4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Sheep and Horse.

Quick Overview for HOXB4 antibody (C-Term) (ABIN2781202)

Target: HOXB4 (Homeobox B4 (HOXB4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Sheep, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXB4 Antibody

Binding Specificity: C-Term

Purpose: HOXB4 Antibody - C-terminal region

Sequence: TRRRRVEIAH ALCLSERQIK IWFQNRRMKW KKDHKLPNTK IRSGGAAGSA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXB4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HOXB4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102704

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXB4

Target: HOXB4 (Homeobox B4 (HOXB4))

Alternative Name: HOXB4

Background:

Background Information: HOXB4 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. The protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.

Gene Name: Homeobox B4

Alternative Symbols: HOX2, HOX2F, HOX-2.6

Protein Name: Homeobox protein Hox-B4

Molecular Weight: 28kDa

Gene ID: 3214

NCBI Accession: NP_076920

UniProt: P17483