DLG3 antibody (Middle Region)

Catalog No. ABIN2781529

Product Details anti-DLG3 Antibody

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FPHKFGSCVP HTTRPRRDNE VDGQDYHFVV SREQMEKDIQ DNKFIEAGQF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DLG3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DLG3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 817 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DLG3 antibody (ABIN2781529)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Alternative Name: DLG3 (DLG3 Products)

Synonyms: MRX antibody, MRX90 antibody, NEDLG antibody, SAP102 antibody, XLMR antibody, DLG3 antibody, fa66c08 antibody, fa66e02 antibody, fd02c12 antibody, fu95c12 antibody, im:7138640 antibody, si:ch211-276g21.1 antibody, wu:fa66c08 antibody, wu:fa66e02 antibody, wu:fd02c12 antibody, wu:fu95c12 antibody, Dlgh3 antibody, mKIAA1232 antibody, MPP3 antibody, 6430514B01 antibody, CSG18 antibody, Dlg3 antibody, Dusp3 antibody, discs large MAGUK scaffold protein 3 antibody, membrane palmitoylated protein 3 antibody, discs, large homolog 3 (Drosophila) antibody, membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) antibody, DLG3 antibody, MPP3 antibody, dlg3 antibody, Dlg3 antibody, Mpp3 antibody

Background: DLG3 is required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90).
Alias Symbols: KIAA1232, MRX, MRX90, NE-Dlg, NEDLG, SAP102, XLMR
Protein Interaction Partner: UBC, BAG3, PPP1CA, KHDRBS1, ELAVL1, DLGAP3, DLGAP4, SYNGAP1, GRIN1, LPHN1, EXOC4, KCNJ12, GDA, SEMA4C, CNKSR2, GLS2, KIF1B, CRIPT, SCN4A, LIN7A, CACNG2, DLG4, MAPK12, GUCY1A2, PTK2B, DLG1, KCNJ2, ERBB4, SCN5A, LRP2, ABCA1, NLGN3, KCNA4, GRIN2C, GRIN2A, GR
Protein Size: 817

Molecular Weight: 90 kDa

Gene ID: 1741

NCBI Accession: NM_021120, NP_066943

UniProt: Q92796