SLC12A3 antibody (Middle Region)

Catalog No. ABIN2781538

The Rabbit Polyclonal anti-SLC12A3 antibody is suitable to detect SLC12A3 in samples from Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SLC12A3 antibody (Middle Region) (ABIN2781538)

Target: SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC12A3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC12A3 Antibody

Binding Specificity: Middle Region

Sequence: ALIVITLPIG RKGKCPSSLY MAWLETLSQD LRPPVILIRG NQENVLTFYC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against SLC12A3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC12A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1030 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC12A3

Target: SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))

Alternative Name: SLC12A3

Background: This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman s
Alias Symbols: NCCT, TSC
Protein Interaction Partner: STIP1, STUB1, UBC, DNAJB1, HSP90AA1, HSPA8, HSPA1A, ACTB, KLHL3, NEDD4, PDIA3, WNK4,
Protein Size: 1030

Molecular Weight: 114 kDa

Gene ID: 6559

NCBI Accession: NM_000339, NP_000330