SLC7A2 antibody (Middle Region)

Catalog No. ABIN2781551

There are 2+ publications for this product available. The Rabbit Polyclonal anti-SLC7A2 antibody is suitable to detect SLC7A2 in samples from Human, Rat, Mouse, Pig, Rabbit, Dog, Cow and Horse. It has been validated for WB.

Quick Overview for SLC7A2 antibody (Middle Region) (ABIN2781551)

Target: SLC7A2 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 2 (SLC7A2))

Reactivity: Human, Rat, Mouse, Pig, Rabbit, Dog, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC7A2 Antibody

Binding Specificity: Middle Region

Sequence: VANWKISEEF LKNISASARE PPSENGTSIY GAGGFMPYGF TGTLAGAATC

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC7A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC7A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 658 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC7A2 antibody (ABIN2781551)

Di Pasqua, Berardo, Rizzo, Richelmi, Croce, Vairetti, Ferrigno: "MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters." in: Molecular and cellular biochemistry, Vol. 419, Issue 1-2, pp. 147-55, (2016) (PubMed).

Kohlhaas, Morrow, Jhakra, Patil, Connell, Petrie, Salt: "Insulin rapidly stimulates L-arginine transport in human aortic endothelial cells via Akt." in: Biochemical and biophysical research communications, Vol. 412, Issue 4, pp. 747-51, (2011) (PubMed).

Target Details for SLC7A2

Target: SLC7A2 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 2 (SLC7A2))

Alternative Name: SLC7A2

Background: SLC7A2 is a low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). SLC7A2 plays a regulatory role in classical or alternative activation of macrophages.
Alias Symbols: ATRC2, CAT-2, HCAT2, CAT2
Protein Interaction Partner: UBC,
Protein Size: 658

Molecular Weight: 72 kDa

Gene ID: 6542

NCBI Accession: NM_001008539, NP_001008539

UniProt: P52569