SLCO1C1 antibody (N-Term)
Quick Overview for SLCO1C1 antibody (N-Term) (ABIN2781650)
Target
See all SLCO1C1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- VDTSSSMWIY VFLGNLLRGI GETPIQPLGI AYLDDFASED NAAFYIGCVQ
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%
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Characteristics
- This is a rabbit polyclonal antibody against SLCO1C1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SLCO1C1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 712 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SLCO1C1 (Solute Carrier Organic Anion Transporter Family, Member 1C1 (SLCO1C1))
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Alternative Name
- SLCO1C1
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Background
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SLCO1C1 is a member of the organic anion transporter family. SLCO1C1 is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism.
Alias Symbols: OATP-F, OATP1, OATP1C1, SLC21A14, OATPF, OATP14, OATPRP5
Protein Interaction Partner: UBC, PDZD3,
Protein Size: 712 -
Molecular Weight
- 79 kDa
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Gene ID
- 53919
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NCBI Accession
- NM_017435, NP_059131
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UniProt
- Q9NYB5
Target
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