NHE7 antibody (N-Term)

Catalog No. ABIN310546

This Rabbit Polyclonal antibody specifically detects NHE7 in WB. It exhibits reactivity toward Human, Mouse, Rabbit, Guinea Pig, Dog, Zebrafish (Danio rerio) and Goat.

Quick Overview for NHE7 antibody (N-Term) (ABIN310546)

Target: NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))

Reactivity: Human, Mouse, Rabbit, Guinea Pig, Dog, Zebrafish (Danio rerio), Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHE7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NHE7 Antibody

Binding Specificity: N-Term

Sequence: LGWGLRVAAA ASASSSGAAA EDSSAMEELA TEKEAEESHR QDSVSLLTFI

Predicted Reactivity: Dog: 100%, Goat: 85%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC9A7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC9A7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 725 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NHE7

Target: NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))

Alternative Name: SLC9A7

Background: Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. It may play an important role in maintaining cation homeostasis and function of the trans-Golgi network.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.
Alias Symbols: NHE7, SLC9A6
Protein Interaction Partner: UBC, SCAMP5, SCAMP2, SCAMP1, SLC9A7,
Protein Size: 725

Molecular Weight: 80 kDa

Gene ID: 84679

NCBI Accession: NM_032591, NP_115980

UniProt: Q96T83