M-CSF/CSF1 antibody (Middle Region)

Catalog No. ABIN2781824

This Rabbit Polyclonal antibody specifically detects M-CSF/CSF1 in WB, IHC and IF. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig and Guinea Pig.

Quick Overview for M-CSF/CSF1 antibody (Middle Region) (ABIN2781824)

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivity: Human, Mouse, Rat, Dog, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This M-CSF/CSF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-M-CSF/CSF1 Antibody

Binding Specificity: Middle Region

Sequence: SGSVLPLGEL EGRRSTRDRR SPAEPEGGPA SEGAARPLPR FNSVPLTDTG

Predicted Reactivity: Dog: 85%, Guinea Pig: 79%, Human: 100%, Mouse: 86%, Pig: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CSF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CSF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 554 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Alternative Name: CSF1

Background: CSF1 is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound
Alias Symbols: MCSF, MGC31930, CSF-1
Protein Interaction Partner: NOTCH2NL, SGTA, FHL3, GAB3, SOCS1, TNF, CSF1R, HLA-B, CSF1, SLA2, UBC, CBL, PIK3R2, SMARCA4,
Protein Size: 554

Molecular Weight: 57 kDa

Gene ID: 1435

NCBI Accession: NM_000757, NP_000748

UniProt: P09603

Pathways: RTK Signaling