KIT Ligand antibody (Middle Region)

Catalog No. ABIN2781827

The Rabbit Polyclonal anti-KIT Ligand antibody has been validated for WB and IHC. It is suitable to detect KIT Ligand in samples from Human, Mouse, Rat, Pig, Dog, Cow, Goat, Horse, Rabbit, Sheep and Guinea Pig.

Quick Overview for KIT Ligand antibody (Middle Region) (ABIN2781827)

Target: KIT Ligand (KITLG)

Reactivity: Human, Mouse, Rat, Pig, Dog, Cow, Goat, Horse, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIT Ligand antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KIT Ligand Antibody

Binding Specificity: Middle Region

Sequence: TKPFMLPPVA ASSLRNDSSS SNRKAKNPPG DSSLHWAAMA LPALFSLIIG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against KITLG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KITLG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 273 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KIT Ligand

Target: KIT Ligand (KITLG)

Alternative Name: KITLG

Background: KITLG is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis.This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp686F2250, KL-1, Kitl, MGF, SCF, SF, FPH2, SHEP7, kit-ligand
Protein Interaction Partner: UBC, CLEC11A, UBE2V1, PIK3CD, FLT3LG, KITLG, KIT, CSF2, EPOR, CMA1,
Protein Size: 273

Molecular Weight: 28 kDa

Gene ID: 4254

NCBI Accession: NM_000899, NP_000890

UniProt: P21583

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway